Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.58 |
| ▸ | BACE1 | P56817 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14235295 | 0.88 | CASP3 (0.57) | CASP3RXFP1KMT2AMEN1CTDSP1 | |
| SCHEMBL6264128 | 0.84 | CASP3 (0.86) | CASP3RXFP1KMT2AMEN1CTDSP1 | |
| SCHEMBL24320985 | 0.84 | KMT2A (0.60) | CASP3RXFP1KMT2AMEN1CTDSP1 | |
| SCHEMBL24320986 | 0.84 | KMT2A (0.60) | CASP3RXFP1KMT2AMEN1CTDSP1 | |
| SCHEMBL24320987 | 0.83 | RXFP1 (0.64) | CASP3RXFP1KMT2AMEN1CTDSP1 | |
| SCHEMBL29355347 | 0.81 | NR1H4 (0.64) | RXFP1KMT2AMEN1NPC1LMNA | |
| SCHEMBL6264004 | 0.80 | KMT2A (0.76) | CASP3RXFP1KMT2AMEN1CTDSP1 | |
| SCHEMBL5639582 | 0.79 | CASP3 (0.66) | CASP3RXFP1KMT2AMEN1POLB | |
| SCHEMBL30949348 | 0.79 | GSK3B (0.67) | CASP3RXFP1KMT2AMEN1CTDSP1 | |
| SCHEMBL31680603 | 0.79 | MAPT (0.58) | CASP3RXFP1KMT2AMEN1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221877-B1 | IN PARTICULAR BOVINE TRICHOMONIASIS AND GIARDIASIS | REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-04-24 | — | — | US | disclosed |
| US-6221877-B1 | IN PARTICULAR BOVINE TRICHOMONIASIS AND GIARDIASIS | REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-04-24 | — | — | US | disclosed |