Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKLR | P30613 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24322524 | 0.86 | NPC1 (0.49) | NPC1RAB9APKMCNR1MAPT | |
| SCHEMBL12626167 | 0.82 | PKM (0.50) | PKMPOLBMAPTSMN1; SMN2LMNA | |
| SCHEMBL12624069 | 0.81 | NPC1 (0.44) | NPC1RAB9APKMCNR1POLB | |
| SCHEMBL13353687 | 0.81 | NPC1 (0.44) | NPC1RAB9APKMCNR1POLB | |
| SCHEMBL31310976 | 0.78 | NPC1 (0.70) | NPC1RAB9APKMCNR1POLB | |
| SCHEMBL24323773 | 0.76 | ALDH1A1 (0.60) | RAB9ASMN1; SMN2KMT2ATP53MEN1 | |
| SCHEMBL12656056 | 0.75 | CCR1 (0.41) | POLBSMN1; SMN2ATMKMT2ATSHR | |
| SCHEMBL12625892 | 0.74 | POLB (0.62) | POLBSMN1; SMN2KMT2AKDM4ETSHR | |
| SCHEMBL12624157 | 0.74 | ALDH1A1 (0.42) | PKMPOLBMAPTSMN1; SMN2LMNA | |
| SCHEMBL20019650 | 0.74 | GLA (0.38) | NPC1RAB9APOLBMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | Psomagen Inc. (US) | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | HTRA1, GIPR, HPN | NPC1 2900/4885RAB9A 435/4885PKM 4535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.