Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24322789 | 0.97 | SMN1; SMN2 (0.48) | SMN1; SMN2RAB9AGAANPC1MAPT | |
| SCHEMBL24323660 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9AGAANPC1MAPT | |
| SCHEMBL24323644 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9AGAANPC1MAPT | |
| SCHEMBL28747806 | 0.79 | FDPS (0.45) | SMN1; SMN2MAPTFDPSMEN1KMT2A | |
| SCHEMBL27916091 | 0.78 | FDPS (0.44) | SMN1; SMN2MAPTFDPSMEN1KMT2A | |
| SCHEMBL1038424 | 0.78 | FDPS (0.44) | SMN1; SMN2MAPTFDPSMEN1KMT2A | |
| SCHEMBL24322395 | 0.78 | FDPS (0.44) | SMN1; SMN2MAPTFDPSMEN1KMT2A | |
| SCHEMBL24322652 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2RAB9AGAANPC1MAPT | |
| SCHEMBL24323854 | 0.76 | NPC1 (0.60) | SMN1; SMN2RAB9AGAANPC1EPHX1 | |
| SCHEMBL24322419 | 0.75 | TDP1 (0.51) | RAB9AGAAEPHX1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | Psomagen Inc. (US) | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | HTRA1, GIPR, HPN | SMN1; SMN2 4226/4885RAB9A 435/4885GAA 1981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.