SCHEMBL2432358

SCHEMBL2432358

O=C(Cc1ccc(-c2ccc(Br)cc2)cc1)Cc1ccc(-c2ccc(Br)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.48
GAA P10253 2/20 0.48
HTT P42858 2/20 0.48
ABCC4 O15439 1/20 0.48
TSHR P16473 1/20 0.48
PTGS1 P23219 1/20 0.48
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
NPC1 O15118 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
HPGD P15428 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
EGFR P00533 1/20 0.46
ERBB2 P04626 1/20 0.46
MAPT P10636 1/20 0.44
ALOX12 P18054 1/20 0.44
RAB9A P51151 1/20 0.44
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 1/20 0.44
PRNP P04156 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1449785 0.93 MEN1 (0.52) LMNAGAAHTTMEN1KMT2A
SCHEMBL10522051 0.88 ALDH1A1 (0.58) LMNAGAAHTTABCC4TSHR
SCHEMBL4201823 0.84 L3MBTL1 (0.62) LMNAHTTMEN1KMT2ASMN1; SMN2
SCHEMBL8173807 0.84 ABCC4 (0.69) LMNAGAAHTTABCC4TSHR
SCHEMBL12002660 0.83 POLB (0.47) LMNAGAAHTTABCC4TSHR
SCHEMBL13432984 0.83 MEN1 (0.44) LMNAGAAHTTMEN1KMT2A
SCHEMBL18371865 0.83 MEN1 (0.64) LMNAMEN1KMT2ANPC1SMN1; SMN2
SCHEMBL6600750 0.82 MEN1 (0.47) LMNAGAAHTTMEN1KMT2A
SCHEMBL5042101 0.82 GSK3B (0.50) LMNAGAAHTTMEN1KMT2A
SCHEMBL28303343 0.82 MKNK1 (0.57) LMNAMAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1476416-B1 MULTIFUNCTIONAL MONOMERS AND THEIR USE IN MAKING CROSS-LINKED POLYMERS AND POROUS FILMS DOW GLOBAL TECHNOLOGIES LLC (US) 2015-12-30 EP disclosed
EP-1758953-B1 METHOD OF FORMING A NANOPOROUS DIELECTRIC FILM DOW GLOBAL TECHNOLOGIES LLC (US) 2011-09-28 EP disclosed
US-7635741-B2 Curable polyacetylenes used as dielectrics in making microelectronics such as integrated circuits DOW GLOBAL TECHNOLOGIES INC. 2009-12-22 US disclosed
US-20080090007-A1 Method Of Forming A Nanoporous Dielectric Film DOW GLOBAL TECHNOLOGIES LLC 2008-04-17 US disclosed
EP-1758953-A1 METHOD OF FORMING A NANOPOROUS DIELECTRIC FILM Dow Gloval Technologies Inc. (US) 2007-03-07 EP disclosed
WO-2006001790-A1 METHOD OF FORMING A NANOPOROUS DIELECTRIC FILM DOW GLOBAL TECHNOLOGIES INC. (US) 2006-01-05 WO disclosed
EP-1476416-A2 MULTIFUNCTIONAL MONOMERS AND THEIR USE IN MAKING CROSS-LINKED POLYMERS AND POROUS FILMS DOW GLOBAL TECHNOLOGIES INC. (US) 2004-11-17 EP disclosed
US-20040053033-A1 Multifunctional monomers and their use in making cross-linked polymers and porous films NIU Q JASON (US) 2004-03-18 US disclosed
WO-2003068825-A2 MULTIFUNCTIONAL MONOMERS AND THEIR USE IN MAKING CROSS-LINKED POLYMERS AND POROUS FILMS DOW GLOBAL TECHNOLOGIES INC. (US) 2003-08-21 WO disclosed
US-5136013-A Polyesters BAYER AKTIENGESELLSCHAFT (DE) 1992-08-04 US disclosed
US-5068300-A BIFUNCTIONAL STILBENE COMPOUNDS CONTAINING AT LEAST ONE Z-CONFIGURATED STILBENE GROUP, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF POLYMERS BAYER AKTIENGESELLSCHAFT (DE) 1991-11-26 US disclosed