Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.67 |
| ▸ | PTPRC | P08575 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL2432364 | 1.00 | SLC7A5 (0.67) | SLC7A5PTPRCPTPN1PTGS1ALPI | |
| Tyrosine SCHEMBL28092675 | 0.96 | SLC7A5 (0.61) | SLC7A5PTPRCPTPN1PTGS1ALPI | |
| SCHEMBL19521372 | 0.91 | FOLH1 (0.52) | SLC7A5CA1CA2FOLH1NAALAD2 | |
| SCHEMBL3626583 | 0.91 | FOLH1 (0.52) | SLC7A5CA1CA2FOLH1NAALAD2 | |
| SCHEMBL7274 | 0.91 | FOLH1 (0.52) | SLC7A5CA1CA2FOLH1NAALAD2 | |
| SCHEMBL1151 | 0.91 | FOLH1 (0.52) | SLC7A5CA1CA2FOLH1NAALAD2 | |
| SCHEMBL3626589 | 0.91 | FOLH1 (0.52) | SLC7A5CA1CA2FOLH1NAALAD2 | |
| Phosphoric Acid SCHEMBL3476884 | 0.90 | FOLH1 (0.51) | SLC7A5CA1CA2FOLH1NAALAD2 | |
| SCHEMBL19615881 | 0.90 | FOLH1 (0.51) | SLC7A5CA1CA2FOLH1NAALAD2 | |
| SCHEMBL18956324 | 0.90 | FOLH1 (0.51) | SLC7A5CA1CA2FOLH1NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045562-B2 | Compositions and methods for modulating lymphocyte activity | WASHINGTON UNIVERSITY (US) | 2015-06-02 | — | — | US | disclosed |
| US-8546541-B2 | Compositions and methods for modulating lymphocyte activity | WASHINGTON UNIVERSITY (US) | 2013-10-01 | — | — | US | disclosed |
| US-20120322986-A1 | COMPOSITIONS AND METHODS FOR MODULATING LYMPHOCYTE ACTIVITY | THE WASHINGTON UNIVERSITY (US) | 2012-12-20 | — | — | US | disclosed |
| US-20120232259-A1 | COMPOSITIONS AND METHODS FOR MODULATING LYMPHOCYTE ACTIVITY | THE WASHINGTON UNIVERSITY (US) | 2012-09-13 | — | — | US | disclosed |
| US-20120214972-A1 | COMPOSITIONS AND METHODS FOR MODULATING LYMPHOCYTE ACTIVITY | THE WASHINGTON UNIVERSITY (US) | 2012-08-23 | — | — | US | disclosed |
| US-20120207759-A1 | COMPOSITIONS AND METHODS FOR MODULATING LYMPHOCYTE ACTIVITY | THE WASHINGTON UNIVERSITY (US) | 2012-08-16 | — | — | US | disclosed |
| US-20110230647-A1 | COMPOSITIONS AND METHODS FOR MODULATING LYMPHOCYTE ACTIVITY | THE WASHINGTON UNIVERSITY (US) | 2011-09-22 | — | — | US | disclosed |
| US-20080269464-A1 | COMPOSITIONS AND METHODS FOR MODULATING LYMPHOCTE ACTIVITY | WASHINGTON UNIVERSITY IN ST. LOUIS (US) | 2008-10-30 | — | — | US | disclosed |
| US-7304149-B2 | BTLA nucleic acids | WASHINGTON UNIVERSITY IN ST. LOUIS (US) | 2007-12-04 | — | — | US | disclosed |
| EP-1539218-A4 | COMPOSITIONS AND METHODS FOR MODULATING LYMPHOCYTE ACTIVITY | UNIV CALIFORNIA (US) | 2007-08-22 | — | — | EP | disclosed |
| US-7157240-B2 | MID 4460, a human tyrosine phosphatase family member and uses therefor | BAYER HEALTHCARE AG (DE) | 2007-01-02 | — | — | US | disclosed |
| EP-1539218-A2 | COMPOSITIONS AND METHODS FOR MODULATING LYMPHOCYTE ACTIVITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-06-15 | — | — | EP | disclosed |
| EP-1427857-A4 | MID 4460, A HUMAN TYROSINE PHOSPHATASE FAMILY MEMBER AND USES THEREFOR | MILLENNIUM PHARM INC (US) | 2005-01-12 | — | — | EP | disclosed |
| US-20040175380-A1 | Compositions and methods for modulating lymphocyte activity | THE WASHINGTON UNIVERSITY | 2004-09-09 | — | — | US | disclosed |
| EP-1427857-A2 | MID 4460, A HUMAN TYROSINE PHOSPHATASE FAMILY MEMBER AND USES THEREFOR | Millennium Pharmaceuticals, Inc. (US) | 2004-06-16 | — | — | EP | disclosed |
| WO-2004000221-A2 | COMPOSITIONS AND METHODS FOR MODULATING LYMPHOCYTE ACTIVITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-12-31 | — | — | WO | disclosed |
| US-20030077638-A1 | MID 4460, a human tyrosine phosphatase family member and uses therefor | MILLENNIUM PHARMACEUTICALS, INC. | 2003-04-24 | — | — | US | disclosed |
| WO-2003025199-A2 | MID 4460, A HUMAN TYROSINE PHOSPHATASE FAMILY MEMBER AND USES THEREFOR | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2003-03-27 | — | — | WO | disclosed |