SCHEMBL3626583

SCHEMBL3626583

O=C(O)C(Cc1ccc(O)cc1)NP(=O)(O)O.O=C(O)C(Cc1ccc(O)cc1)NP(=O)(O)O

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.52
NAALAD2 Q9Y3Q0 1/20 0.52
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
SLC7A5 Q01650 1/20 0.50
MME P08473 6/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
ACE P12821 6/20 0.48
CPA1 P15085 1/20 0.48
ACE2 Q9BYF1 1/20 0.48
ECE1 P42892 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3626589 1.00 FOLH1 (0.52) FOLH1NAALAD2CA1CA2SLC7A5
SCHEMBL1151 1.00 FOLH1 (0.52) FOLH1NAALAD2CA1CA2SLC7A5
SCHEMBL7274 1.00 FOLH1 (0.52) FOLH1NAALAD2CA1CA2SLC7A5
SCHEMBL19521372 1.00 FOLH1 (0.52) FOLH1NAALAD2CA1CA2SLC7A5
SCHEMBL18956324 0.98 FOLH1 (0.51) FOLH1NAALAD2CA1CA2SLC7A5
Phosphoric Acid SCHEMBL3476884 0.98 FOLH1 (0.51) FOLH1NAALAD2CA1CA2SLC7A5
SCHEMBL19615881 0.98 FOLH1 (0.51) FOLH1NAALAD2CA1CA2SLC7A5
SCHEMBL5583127 0.94 FOLH1 (0.48) FOLH1NAALAD2CA1CA2SLC7A5
SCHEMBL7711554 0.94 FOLH1 (0.48) FOLH1NAALAD2CA1CA2SLC7A5
Tyrosine SCHEMBL2432370 0.91 SLC7A5 (0.67) FOLH1NAALAD2CA1CA2SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2142651-A2 METHOD FOR RAPIDLY SCREENING MICROBIAL HOSTS TO IDENTIFY CERTAIN STRAINS WITH IMPROVED YIELD AND/OR QUALITY IN THE EXPRESSION OF HETEROLOGOUS PROTEINS Dow Global Technologies Inc. (US) 2010-01-13 EP disclosed
WO-2008134461-A2 METHOD FOR RAPIDLY SCREENING MICROBIAL HOSTS TO IDENTIFY CERTAIN STRAINS WITH IMPROVED YIELD AND/OR QUALITY IN THE EXPRESSION OF HETEROLOGOUS PROTEINS DOW GLOBAL TECHNOLOGIES, INC. (US) 2008-11-06 WO disclosed