SCHEMBL24323784

SCHEMBL24323784

CNCCN1CCN(Cc2ccc(F)cc2)CC1

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.59
PRMT6 Q96LA8 1/20 0.59
MAPK1 P28482 2/20 0.50
MAPT P10636 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
KDM4E B2RXH2 1/20 0.49
NCF1 P14598 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24322836 0.87 CARM1 (0.59) CARM1PRMT6TAAR1
SCHEMBL6957735 0.83 MC4R (0.65) CARM1PRMT6
SCHEMBL8117468 0.82 MAPT (0.67) MAPK1MAPTKDM4E
SCHEMBL1507008 0.80 LMNA (0.67) PRMT6MAPTKDM4ENCF1
SCHEMBL10686392 0.80 SIGMAR1 (0.60) MAPTKDM4E
SCHEMBL8328840 0.80 CARM1 (0.42) CARM1PRMT6MAPK1MAPT
SCHEMBL24322486 0.80 KCNJ1 (0.57) MAPK1NCF1
SCHEMBL9096825 0.79 MAPT (0.56) MAPTKDM4E
Hydrochloric Acid SCHEMBL10502749 0.79 SIGMAR1 (0.59) MAPTKDM4E
SCHEMBL23751084 0.78 MAPK1 (0.55) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220122691-A1 HtrA Inhibitors and CagA Inhibitors and Use Thereof Psomagen Inc. (US) 2022-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220122691-A1 HtrA Inhibitors and CagA Inhibitors and Use Thereof HTRA1, GIPR, HPN CARM1 4394/4885PRMT6 2880/4885MAPK1 1762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.