Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | JAK3 | P52333 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1441662 | 0.82 | ALDH1A1 (0.54) | POLBTSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7282380 | 0.80 | POLB (0.59) | POLBTSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5751507 | 0.79 | ALDH1A1 (0.75) | TSHRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL793647 | 0.79 | ALDH1A1 (0.68) | POLBALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6518077 | 0.79 | DRD4 (0.65) | POLBTSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24322776 | 0.78 | ALDH1A1 (0.70) | POLBTSHRCYP3A4CYP2D6MAPT | |
| Hydrochloric Acid SCHEMBL210978 | 0.77 | ALDH1A1 (0.67) | POLBALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13595586 | 0.77 | KDM4E (0.52) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10775964 | 0.77 | SMN1; SMN2 (0.72) | POLBTSHRMAPTALDH1A1MEN1 | |
| SCHEMBL15630650 | 0.76 | POLB (0.55) | POLBTSHRCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | Psomagen Inc. (US) | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | HTRA1, GIPR, HPN | POLB 4461/4885TSHR 1902/4885CYP1A2 4765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.