Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.57 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.57 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.57 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24322526 | 0.82 | ALDH1A1 (0.74) | ALDH1A1TSHRL3MBTL1CYP3A4GAA | |
| SCHEMBL24323801 | 0.78 | POLB (0.61) | ALDH1A1KDM4ETSHRPOLBCYP3A4 | |
| SCHEMBL10914817 | 0.77 | ALDH1A1 (0.71) | ALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL1442840 | 0.77 | POLB (0.55) | ALDH1A1KDM4ETSHRHSD17B10POLB | |
| Hydrochloric Acid SCHEMBL10911639 | 0.76 | ALDH1A1 (0.70) | ALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL7288865 | 0.75 | KMT2A (0.73) | ALDH1A1KDM4ETSHRPOLBGAA | |
| SCHEMBL1646834 | 0.75 | ALDH1A1 (0.76) | ALDH1A1TSHRL3MBTL1POLBCYP3A4 | |
| SCHEMBL793647 | 0.75 | ALDH1A1 (0.68) | ALDH1A1KDM4ECHRNB2CHRNB4CHRNA3 | |
| SCHEMBL2561097 | 0.74 | ALDH1A1 (0.63) | ALDH1A1KDM4ETSHRHSD17B10L3MBTL1 | |
| SCHEMBL10914678 | 0.74 | ALDH1A1 (0.72) | ALDH1A1KDM4ETSHRHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | Psomagen Inc. (US) | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | HTRA1, GIPR, HPN | ALDH1A1 4556/4885KDM4E 4426/4885TSHR 1902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.