Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.76 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 6/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23027807 | 0.88 | LMNA (1.00) | LMNASMN1; SMN2L3MBTL1RXFP1ALDH1A1 | |
| SCHEMBL23027822 | 0.86 | LMNA (0.83) | LMNASMN1; SMN2L3MBTL1RXFP1ALDH1A1 | |
| SCHEMBL23027810 | 0.86 | SMN1; SMN2 (1.00) | LMNASMN1; SMN2L3MBTL1RXFP1ALDH1A1 | |
| SCHEMBL23027798 | 0.84 | LMNA (0.78) | LMNASMN1; SMN2L3MBTL1RXFP1ALDH1A1 | |
| SCHEMBL23027811 | 0.80 | LMNA (1.00) | LMNASMN1; SMN2L3MBTL1RXFP1ALDH1A1 | |
| SCHEMBL23027787 | 0.75 | POLB (0.84) | LMNASMN1; SMN2L3MBTL1RXFP1ALDH1A1 | |
| SCHEMBL23027794 | 0.75 | LMNA (0.65) | LMNASMN1; SMN2L3MBTL1RXFP1ALDH1A1 | |
| SCHEMBL23027836 | 0.74 | LMNA (0.61) | LMNASMN1; SMN2L3MBTL1RXFP1ALDH1A1 | |
| SCHEMBL17261495 | 0.74 | PKM (0.72) | LMNASMN1; SMN2L3MBTL1RXFP1ALDH1A1 | |
| SCHEMBL29451720 | 0.73 | PKM (0.70) | LMNASMN1; SMN2L3MBTL1RXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3960171-A1 | USE OF ADAM9 INHIBITOR AS IMMUNOMODULATOR | China Medical University (TW) | 2022-03-02 | — | — | EP | disclosed |