SCHEMBL24325877

SCHEMBL24325877

C=C(C)C(=O)OCc1cc(C)c(O)c(I)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 7/20 0.36
PPARG P37231 5/20 0.36
THRA P10827 5/20 0.36
RXRA P19793 2/20 0.36
ITGB3 P05106 1/20 0.36
ITGAV P06756 1/20 0.36
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
LMNA P02545 2/20 0.35
TTR P02766 2/20 0.35
ADORA3 P0DMS8 2/20 0.35
PDE4D Q08499 2/20 0.35
HSD17B10 Q99714 2/20 0.35
ALDH1A1 P00352 2/20 0.35
NR1I2 O75469 2/20 0.35
NR3C1 P04150 1/20 0.35
CYP1A2 P05177 1/20 0.35
HTR1A P08908 1/20 0.35
CYP2C9 P11712 1/20 0.35
TBXA2R P21731 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22176877 0.94 THRB (0.40) THRBPPARGTHRARXRAITGB3
SCHEMBL9315914 0.91 TSHR (0.39) THRBMEN1KMT2AALDH1A1CYP1A2
SCHEMBL24106131 0.84 MET (0.46) LMNA
SCHEMBL23001324 0.80 TSHR (0.36) THRBPPARGTHRARXRAITGB3
SCHEMBL18904501 0.79 TSHR (0.40) THRBLMNAALDH1A1TSHRESR1
SCHEMBL24106184 0.79 ESR1 (0.40) THRBPPARGTHRARXRAMEN1
SCHEMBL25571437 0.79 POLB (0.36) THRBPPARGTHRARXRAITGB3
SCHEMBL22176796 0.79 TTR (0.42) THRBPPARGTHRARXRAITGB3
SCHEMBL7922433 0.79 HSP90AB1 (0.44) THRBLMNAALDH1A1CYP3A4PTGS2
SCHEMBL23001325 0.78 TSHR (0.37) THRBKMT2AHSD17B10ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230174688-A1 COMPOUND, (CO)POLYMER, COMPOSITION, METHOD FOR FORMING RESIST PATTERN, METHOD FOR PRODUCING COMPOUND, AND METHOD FOR PRODUCING (CO)POLYMER MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-06-08 US disclosed
US-20220119336-A1 COMPOUND, (CO)POLYMER, COMPOSITION, METHOD FOR FORMING PATTERN, AND METHOD FOR PRODUCING COMPOUND MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2022-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230174688-A1 COMPOUND, (CO)POLYMER, COMPOSITION, METHOD FOR FORMING RESIST PATTERN, METHOD FOR PRODUCING COMPOUND, AND METHOD FOR PRODUCING (CO)POLYMER MCCC2, MMAB, INTS9 THRB 551/4885PPARG 2251/4885THRA 496/4885
US-20220119336-A1 COMPOUND, (CO)POLYMER, COMPOSITION, METHOD FOR FORMING PATTERN, AND METHOD FOR PRODUCING COMPOUND PYM1, MMAB, MEN1 THRB 941/4885PPARG 4183/4885THRA 782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.