Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10238797 | 0.77 | DRD2 (0.40) | DRD2DRD1PDK2PDK4 | |
| SCHEMBL21097488 | 0.75 | DRD2 (0.39) | DRD2DRD1PDK2PDK4 | |
| SCHEMBL24336496 | 0.72 | DRD2 (0.37) | DRD2DRD1PDK2PDK4SSTR4 | |
| SCHEMBL16692275 | 0.70 | DRD2 (0.38) | DRD2DRD1PDK2PDK4 | |
| SCHEMBL24335928 | 0.70 | PDPK1 (0.53) | PDPK1PDK2 | |
| SCHEMBL16619711 | 0.70 | PDPK1 (0.53) | PDPK1PDK2 | |
| SCHEMBL20840970 | 0.69 | DRD2 (0.37) | DRD2DRD1PDK2PDK4ACHE | |
| SCHEMBL26571108 | 0.69 | DRD2 (0.37) | DRD2DRD1PDK2PDK4 | |
| SCHEMBL10376879 | 0.69 | DRD2 (0.37) | DRD2DRD1PDK2PDK4 | |
| SCHEMBL10376874 | 0.69 | UGT2B17 (0.53) | DRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022063197-A1 | PYRIMIDINE CARBOXAMIDE COMPOUND AND APPLICATION THEREOF | 上海美悦生物科技发展有限公司 | 2022-03-31 | — | — | WO | disclosed |