Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24326976 | 0.86 | HTR2C (0.38) | NPSR1NPBWR1MCHR1GPR55HTR2C | |
| SCHEMBL24327448 | 0.81 | MEN1 (0.36) | NPSR1NPBWR1MCHR1GPR55HTR2C | |
| SCHEMBL24326968 | 0.81 | HTR2C (0.35) | NPSR1NPBWR1MCHR1GPR55HTR2A | |
| SCHEMBL26779501 | 0.80 | TP53 (0.35) | NPSR1HTR2AHTR2CHTR2BNOTUM | |
| SCHEMBL24351831 | 0.79 | HTR2C (0.40) | NPSR1NPBWR1MCHR1GPR55HTR2C | |
| SCHEMBL24351816 | 0.78 | KDM4E (0.34) | NPSR1NPBWR1MCHR1GPR55HTR2A | |
| SCHEMBL24326972 | 0.78 | HTR2C (0.40) | HTR2CHTR2BMEN1KMT2ANOTUM | |
| SCHEMBL24351819 | 0.77 | HTR2A (0.39) | NPSR1HTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL24351832 | 0.77 | HTR6 (0.41) | NPSR1HTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL26777769 | 0.72 | HTR2C (0.33) | NPSR1NPBWR1MCHR1GPR55HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022063106-A1 | INDOLINE COMPOUNDS AND DERIVATIVES AS EGFR INHIBITORS | BEIGENE, LTD. (KY) | 2022-03-31 | — | — | WO | disclosed |