Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22180334 | 0.89 | HSD11B1 (0.34) | ALDH1A1GBA1HSD11B1KDM1A | |
| SCHEMBL23588916 | 0.84 | GBA1 (0.39) | GBA1HSD11B1 | |
| SCHEMBL26778307 | 0.81 | CYP1A2 (0.43) | GBA1HSD11B1 | |
| SCHEMBL30674981 | 0.80 | HSD11B1 (0.36) | ALDH1A1GBA1HSD11B1 | |
| SCHEMBL20231747 | 0.80 | GBA1 (0.37) | ALDH1A1GBA1HSD11B1 | |
| SCHEMBL23588749 | 0.78 | — | — | |
| SCHEMBL24854246 | 0.78 | — | — | |
| SCHEMBL25810196 | 0.77 | HSD11B1 (0.40) | ALDH1A1HSD11B1 | |
| SCHEMBL15986910 | 0.77 | ALOX15 (0.36) | — | |
| SCHEMBL15986911 | 0.74 | ALOX15 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022063106-A1 | INDOLINE COMPOUNDS AND DERIVATIVES AS EGFR INHIBITORS | BEIGENE, LTD. (KY) | 2022-03-31 | — | — | WO | disclosed |