Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 20/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 19/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 13/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13673559 | 1.00 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL615680 | 0.90 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3KCNH2 | |
| Acetic Acid SCHEMBL9471385 | 0.85 | SLC6A4 (0.41) | SLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL16408232 | 0.85 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL16408333 | 0.85 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL30419345 | 0.85 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL18872575 | 0.85 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL25676929 | 0.84 | CHRNB2 (0.39) | SLC6A4SLC6A2SLC6A3KCNH2 | |
| Hydrochloric Acid SCHEMBL15808506 | 0.81 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL11616 | 0.81 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219479-A1 | PYRIMIDINE CARBOXAMIDE COMPOUND AND APPLICATION THEREOF | Shanghai Meiyue Biotech Development Co., Ltd. (CN) | 2023-08-02 | — | — | EP | disclosed |
| WO-2022063197-A1 | PYRIMIDINE CARBOXAMIDE COMPOUND AND APPLICATION THEREOF | 上海美悦生物科技发展有限公司 | 2022-03-31 | — | — | WO | disclosed |
| WO-2022063333-A1 | PYRIMIDINE CARBOXAMIDE COMPOUND AND APPLICATION THEREOF | 上海美悦生物科技发展有限公司 | 2022-03-31 | — | — | WO | disclosed |
| CN-109563136-A | Cyclic peptide as C5a receptor antagonist | 辉瑞公司 | 2019-04-02 | — | — | CN | disclosed |