Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 17/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 16/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17961728 | 1.00 | SLC6A4 (0.46) | SLC6A4SLC6A2KCNH2SLC6A3CYP3A4 | |
| SCHEMBL17961761 | 1.00 | SLC6A4 (0.46) | SLC6A4SLC6A2KCNH2SLC6A3CYP3A4 | |
| Hydrochloric Acid SCHEMBL21772854 | 0.98 | SLC6A4 (0.44) | SLC6A4SLC6A2KCNH2SLC6A3CYP3A4 | |
| SCHEMBL21772847 | 0.93 | SLC6A4 (0.44) | SLC6A4SLC6A2KCNH2SLC6A3CYP2D6 | |
| Hydrochloric Acid SCHEMBL28595890 | 0.91 | SLC6A4 (0.43) | SLC6A4SLC6A2KCNH2SLC6A3CYP2D6 | |
| SCHEMBL15421980 | 0.89 | SLC6A1 (0.44) | SLC6A4SLC6A2KCNH2SLC6A3CYP2D6 | |
| SCHEMBL12141653 | 0.88 | GABRP (0.41) | SLC6A4SLC6A2KCNH2SLC6A3CYP2D6 | |
| SCHEMBL30419392 | 0.86 | SLC6A4 (0.42) | SLC6A4SLC6A2KCNH2SLC6A3CYP3A4 | |
| SCHEMBL17961750 | 0.86 | CHRNB2 (0.38) | SLC6A4SLC6A2KCNH2 | |
| SCHEMBL25565972 | 0.84 | GABRP (0.46) | SLC6A4SLC6A2KCNH2SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3030557-B1 | A NOVEL PHTALAZINONE DERIVATIVES AND MANUFACTURING PROCESS THEREOF | IDIENCE CO LTD (KR) | 2023-05-31 | — | — | EP | disclosed |
| US-RE49338-E1 | Phthalazinone derivatives and manufacturing process thereof | IDIENCE CO., LTD. (KR) | 2022-12-20 | — | — | US | disclosed |
| US-9844550-B2 | Phtalazinone derivatives and manufacturing process thereof | ILDONG PHARM CO., LTD (KR) | 2017-12-19 | — | — | US | disclosed |
| US-20170182045-A1 | Novel Phtalazinone Derivatives and Manufacturing Process Thereof | IL DONG HOLDINGS CO., LTD (KR) | 2017-06-29 | — | — | US | disclosed |
| US-9682973-B2 | Phtalazinone derivatives and manufacturing process thereof | ILDONG PHARM CO., LTD (KR) | 2017-06-20 | — | — | US | disclosed |
| US-20160222003-A1 | Novel Phtalazinone Derivatives and Manufacturing Process Thereof | IL DONG HOLDINGS CO., LTD (KR) | 2016-08-04 | — | — | US | disclosed |
| WO-2011066211-A1 | AZABENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160222003-A1 | Novel Phtalazinone Derivatives and Manufacturing Process Thereof | PARP15, PARP10, PARP1 | SLC6A4 4250/4885SLC6A2 4664/4885KCNH2 4100/4885 |
| US-20170182045-A1 | Novel Phtalazinone Derivatives and Manufacturing Process Thereof | PARP15, PARP10, NUDT5 | SLC6A4 3692/4885SLC6A2 4431/4885KCNH2 2825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.