Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TTK | P33981 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 3/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327768 | 0.82 | AHR (0.42) | AHREP300KCNH2TTKCNR1 | |
| SCHEMBL29738275 | 0.72 | AHR (0.44) | AHRTTKCNR1CNR2PFKFB3 | |
| SCHEMBL29738270 | 0.72 | AHR (0.44) | AHRTTKCNR1CNR2PFKFB3 | |
| SCHEMBL24327387 | 0.68 | AHR (0.42) | AHREP300TTKCNR1CNR2 | |
| SCHEMBL24327400 | 0.68 | AHR (0.41) | AHREP300TTKCNR1CNR2 | |
| SCHEMBL29601453 | 0.68 | JAK2 (0.44) | AHREP300TTKCNR1CNR2 | |
| SCHEMBL24327328 | 0.68 | JAK2 (0.44) | AHREP300TTKCNR1CNR2 | |
| SCHEMBL24327399 | 0.68 | AHR (0.41) | AHREP300KCNH2TTKCNR1 | |
| SCHEMBL24327333 | 0.68 | JAK2 (0.44) | AHREP300TTKCNR1CNR2 | |
| SCHEMBL29498955 | 0.67 | KDR (0.45) | KCNH2KITKDRLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078356-A1 | HETEROAROMATIC AHR INHIBITOR | 山东轩竹医药科技有限公司 | 2022-04-21 | — | — | WO | disclosed |