SCHEMBL24328216

SCHEMBL24328216

CNCCNC(=O)C(CC(=O)C(C)(C)C)NC(=O)C(C)(C)C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 1/20 0.36
TACR3 P29371 1/20 0.36
GRIA1 P42261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20623017 0.90 GRIA1 (0.37) TACR1TACR3GRIA1
SCHEMBL21536833 0.86 GRIA1 (0.37) TACR1TACR3GRIA1
SCHEMBL24328660 0.83 KDM4E (0.34)
SCHEMBL20623016 0.80 TACR1 (0.33) TACR1TACR3
SCHEMBL24823972 0.78 TACR1 (0.32) TACR1TACR3
SCHEMBL19756282 0.75 GRIA1 (0.44) TACR1TACR3GRIA1
SCHEMBL21285433 0.73
SCHEMBL19756273 0.72 KDM4E (0.36) GRIA1
SCHEMBL22390106 0.72 USP2 (0.34) TACR1TACR3
SCHEMBL19115834 0.67 SIRT6 (0.40) TACR1TACR3GRIA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220118053-A1 Dry Pharmaceutical Formulations of CNP Conjugates ASCENDIS PHARMA GROWTH DISORDERS A/S (DK) 2022-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220118053-A1 Dry Pharmaceutical Formulations of CNP Conjugates CNP, PTMS, NPPA TACR1 164/4885TACR3 137/4885GRIA1 2197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.