SCHEMBL24328223

SCHEMBL24328223

N#Cc1ccc2c(CI)c[nH]c2c1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 6/20 0.46
NR3C1 P04150 1/20 0.45
PGR P06401 1/20 0.45
NR3C2 P08235 1/20 0.45
BCHE P06276 1/20 0.45
IDO1 P14902 1/20 0.44
CDK2 P24941 3/20 0.43
GPR84 Q9NQS5 2/20 0.41
HTR2A P28223 1/20 0.41
DRD2 P14416 1/20 0.40
DRD4 P21917 1/20 0.40
DRD3 P35462 1/20 0.40
GUSB P08236 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24328228 0.87 SLC6A4 (0.59) SLC6A4DRD2DRD4DRD3
SCHEMBL13497718 0.81 SLC6A4 (0.53) SLC6A4NR3C1PGRNR3C2BCHE
SCHEMBL2539430 0.81 HTR2A (0.65) SLC6A4HTR2ADRD3
SCHEMBL31573289 0.81 HTR2A (0.65) SLC6A4HTR2ADRD3
SCHEMBL15678339 0.80 SLC6A4 (0.56) SLC6A4NR3C1PGRNR3C2BCHE
SCHEMBL26941656 0.80 NR3C1 (0.47) SLC6A4NR3C1PGRNR3C2BCHE
SCHEMBL6238687 0.78 ALDH1A1 (0.52) SLC6A4NR3C1PGRNR3C2BCHE
SCHEMBL14350588 0.77 HTR2A (0.65) NR3C1NR3C2IDO1GPR84HTR2A
SCHEMBL6039798 0.77 IDO1 (0.47) SLC6A4IDO1GUSB
SCHEMBL25139569 0.77 CDK2 (0.47) SLC6A4NR3C1PGRNR3C2BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022078416-A1 NOVEL GLUTAMINE ANALOGS JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2022-04-21 WO disclosed