Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 3/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2433943 | 0.81 | MAPT (0.48) | ITGB1ITGA4MAPTTP53SMN1; SMN2 | |
| SCHEMBL2432642 | 0.81 | EPHB3 (0.54) | ITGB1ITGA4FLT3 | |
| SCHEMBL91533 | 0.81 | ITGB1 (0.47) | ITGB1ITGA4RAB9AMAPTMEN1 | |
| SCHEMBL2433516 | 0.80 | KDM4E (0.45) | TSHRALDH1A1KDM4EHDAC3HDAC1 | |
| SCHEMBL2440170 | 0.79 | ITGB1 (0.58) | ITGB1ITGA4RAB9AMAPTMEN1 | |
| SCHEMBL27581128 | 0.79 | ITGB1 (0.46) | ITGB1ITGA4RAB9AMAPTMEN1 | |
| SCHEMBL14591890 | 0.79 | ITGB1 (0.54) | ITGB1ITGA4RAB9AMAPTMEN1 | |
| SCHEMBL14626747 | 0.79 | ITGB1 (0.55) | ITGB1ITGA4RAB9AMAPTMEN1 | |
| SCHEMBL2435623 | 0.77 | NR1I2 (0.40) | RAB9AKMT2ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL14491705 | 0.77 | ITGB1 (0.55) | ITGB1ITGA4RAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346982-B1 | VLA-4 INHIBITORS | DAIICHI SEIYAKU CO (JP) | 2011-09-14 | — | — | EP | disclosed |