Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 9/20 | 0.46 |
| ▸ | LMNA | P02545 | 7/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2432642 | 0.83 | EPHB3 (0.54) | ITGB1ITGA4 | |
| SCHEMBL2432847 | 0.81 | ITGB1 (0.46) | MAPTTP53ITGB1ITGA4SMN1; SMN2 | |
| SCHEMBL92550 | 0.81 | MAPT (0.59) | MAPTPOLBTP53LMNASMN1; SMN2 | |
| SCHEMBL2433516 | 0.80 | KDM4E (0.45) | — | |
| SCHEMBL2431349 | 0.79 | ITGB1 (0.58) | MAPTPOLBTP53LMNAITGB1 | |
| SCHEMBL14591879 | 0.79 | ITGB1 (0.54) | MAPTPOLBTP53LMNAITGB1 | |
| SCHEMBL14626739 | 0.79 | ITGB1 (0.55) | MAPTPOLBTP53LMNAITGB1 | |
| SCHEMBL2435623 | 0.77 | NR1I2 (0.40) | POLBTP53LMNASMN1; SMN2 | |
| SCHEMBL92543 | 0.75 | MAPT (0.63) | MAPTPOLBTP53LMNASMN1; SMN2 | |
| SCHEMBL2430353 | 0.74 | PTGER4 (0.53) | MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346982-B1 | VLA-4 INHIBITORS | DAIICHI SEIYAKU CO (JP) | 2011-09-14 | — | — | EP | disclosed |