Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHB3 | P54753 | 1/20 | 0.54 |
| ▸ | FLT3 | P36888 | 8/20 | 0.47 |
| ▸ | CDK2 | P24941 | 2/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | ITK | Q08881 | 4/20 | 0.45 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.44 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2433943 | 0.83 | MAPT (0.48) | ITGB1ITGA4 | |
| SCHEMBL2432847 | 0.81 | ITGB1 (0.46) | FLT3ITGB1ITGA4 | |
| SCHEMBL2433516 | 0.80 | KDM4E (0.45) | — | |
| SCHEMBL2432131 | 0.79 | EPHB3 (0.60) | EPHB3FLT3CDK2CCNA2CCNA1 | |
| SCHEMBL14591889 | 0.79 | EPHB3 (0.56) | EPHB3FLT3CDK2CCNA2CCNA1 | |
| SCHEMBL14626754 | 0.79 | EPHB3 (0.58) | EPHB3FLT3CDK2CCNA2CCNA1 | |
| SCHEMBL27596530 | 0.78 | EPHB3 (0.61) | EPHB3FLT3CDK2CCNA2CCNA1 | |
| SCHEMBL2435623 | 0.77 | NR1I2 (0.40) | — | |
| SCHEMBL14592698 | 0.77 | ITGB1 (0.56) | EPHB3FLT3CDK2CCNA2CCNA1 | |
| SCHEMBL27578649 | 0.77 | EPHB3 (0.58) | EPHB3FLT3CDK2CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346982-B1 | VLA-4 INHIBITORS | DAIICHI SEIYAKU CO (JP) | 2011-09-14 | — | — | EP | disclosed |