Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 7/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 7/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24352114 | 0.81 | MTNR1A (0.40) | CARM1PRMT6PRMT8 | |
| SCHEMBL24327351 | 0.81 | CARM1 (0.36) | CARM1PRMT6PRMT8ALDH1A1HTT | |
| SCHEMBL24327498 | 0.77 | TIPARP (0.34) | ALDH1A1HTT | |
| SCHEMBL29661397 | 0.77 | TIPARP (0.34) | ALDH1A1HTT | |
| SCHEMBL12862621 | 0.75 | L3MBTL1 (0.43) | ALDH1A1HTT | |
| SCHEMBL29661478 | 0.75 | KDM4E (0.49) | ALDH1A1HTT | |
| SCHEMBL24328562 | 0.75 | KDM4E (0.49) | ALDH1A1HTT | |
| SCHEMBL29661314 | 0.74 | KDM4E (0.38) | ALDH1A1HTT | |
| SCHEMBL24327660 | 0.74 | KDM4E (0.38) | ALDH1A1HTT | |
| SCHEMBL23259863 | 0.67 | CARM1 (0.45) | CARM1PRMT6PRMT8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022063106-A1 | INDOLINE COMPOUNDS AND DERIVATIVES AS EGFR INHIBITORS | BEIGENE, LTD. (KY) | 2022-03-31 | — | — | WO | disclosed |