Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4858286 | 0.89 | KDM4E (0.50) | — | |
| SCHEMBL17065543 | 0.89 | KDM4E (0.50) | — | |
| SCHEMBL20570539 | 0.89 | — | — | |
| SCHEMBL23567016 | 0.89 | KDM4E (0.50) | — | |
| SCHEMBL22749162 | 0.89 | KDM4E (0.50) | — | |
| SCHEMBL23926540 | 0.89 | KDM4E (0.50) | — | |
| SCHEMBL22581617 | 0.89 | KDM4E (0.50) | — | |
| SCHEMBL20570026 | 0.89 | KDM4E (0.50) | — | |
| SCHEMBL20570963 | 0.89 | KDM4E (0.50) | — | |
| SCHEMBL1865619 | 0.89 | KDM4E (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10328425-B2 | Functionalized main chain polymers | HAERING THOMAS (DE) | 2019-06-25 | — | — | US | disclosed |
| US-20170266652-A1 | FUNCTIONALIZED MAIN CHAIN POLYMERS | HÄRING THOMAS (DE) | 2017-09-21 | — | — | US | disclosed |
| US-20170095809-A1 | FUNCTIONALIZED MAIN CHAIN POLYMERS | HÄRING THOMAS (DE) | 2017-04-06 | — | — | US | disclosed |
| US-20140155502-A1 | FUNCTIONALIZED MAIN CHAIN POLYMERS | Häring, Thomas (DE) | 2014-06-05 | — | — | US | disclosed |
| US-8710175-B2 | Functionalized main chain polymers | Häring, Thomas (DE) | 2014-04-29 | — | — | US | disclosed |
| US-20120004330-A1 | FUNCTIONALIZED MAIN CHAIN POLYMERS | HAERING THOMAS (DE) | 2012-01-05 | — | — | US | disclosed |
| US-20100081783-A1 | Functionalized Main Chain Polymers | HARING THOMAS | 2010-04-01 | — | — | US | disclosed |
| US-7615599-B2 | Noncrosslinked, covalently crosslinked and/or ionically crosslinked polymer which can be used in direct methanol fuel cells; sulfonated polyetherketones and sulfonated polysulfones; acid doped polymer has high mechanical stability and a low permeability for hydrogen, oxygen and methanol | HAERING THOMAS | 2009-11-10 | — | — | US | disclosed |
| US-20070208153-A1 | Functionalized Main Chain Polymers | HARING THOMAS | 2007-09-06 | — | — | US | disclosed |
| US-7196151-B2 | Functionalized main chain polymers | HAERING THOMAS | 2007-03-27 | — | — | US | disclosed |
| US-20050124769-A1 | Noncrosslinked, covalently crosslinked and/or ionically crosslinked polymer which can be used in direct methanol fuel cells; acid doped polymer has high mechanical stability and a low permeability for hydrogen, oxygen and methanol | HARING THOMAS (DE) | 2005-06-09 | — | — | US | disclosed |