Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 2/20 | 0.40 |
| ▸ | INSR | P06213 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24329029 | 0.87 | HPGD (0.62) | HPGDKMT2AMEN1KDM2BTP53 | |
| SCHEMBL23675179 | 0.84 | HPGD (1.00) | HPGDALDH1A1 | |
| SCHEMBL24329026 | 0.78 | HPGD (0.58) | HPGDKMT2AMEN1TP53MAPT | |
| SCHEMBL23675143 | 0.76 | HPGD (0.84) | HPGDALDH1A1 | |
| SCHEMBL24463679 | 0.75 | HPGD (0.83) | HPGDALDH1A1 | |
| SCHEMBL24463674 | 0.74 | HPGD (1.00) | HPGDALDH1A1 | |
| SCHEMBL24328710 | 0.73 | HPGD (0.79) | HPGDKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL23675292 | 0.71 | HPGD (0.84) | HPGDKMT2AMEN1TP53MAPT | |
| SCHEMBL29995196 | 0.71 | HPGD (0.84) | HPGDKMT2AMEN1TP53MAPT | |
| SCHEMBL6469077 | 0.71 | ITK (0.50) | ITKINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022082009-A1 | INHALED FORMULATIONS OF PGDH INHIBITORS AND METHODS OF USE THEREOF | EPIRIUM BIO INC. (US) | 2022-04-21 | — | — | WO | disclosed |