Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24329027 | 0.87 | HPGD (0.73) | HPGDMAPTKMT2AMEN1TP53 | |
| SCHEMBL23675292 | 0.85 | HPGD (0.84) | HPGDMAPTKMT2AMEN1TP53 | |
| SCHEMBL29995196 | 0.85 | HPGD (0.84) | HPGDMAPTKMT2AMEN1TP53 | |
| SCHEMBL23675307 | 0.77 | HPGD (1.00) | HPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL24328710 | 0.77 | HPGD (0.79) | HPGDMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL24329026 | 0.75 | HPGD (0.58) | HPGDMAPTKMT2AMEN1TP53 | |
| SCHEMBL24463679 | 0.73 | HPGD (0.83) | HPGDALDH1A1 | |
| SCHEMBL23675143 | 0.72 | HPGD (0.84) | HPGDALDH1A1 | |
| SCHEMBL23675179 | 0.71 | HPGD (1.00) | HPGDALDH1A1 | |
| SCHEMBL3062222 | 0.70 | MEN1 (0.64) | MAPTKMT2AMEN1TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022082009-A1 | INHALED FORMULATIONS OF PGDH INHIBITORS AND METHODS OF USE THEREOF | EPIRIUM BIO INC. (US) | 2022-04-21 | — | — | WO | disclosed |