Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 14/20 | 0.34 |
| ▸ | WNT1 | P04628 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24328727 | 0.86 | HPGD (0.34) | HPGDIRAK4WNT1GSK3BDYRK1A | |
| SCHEMBL24328728 | 0.85 | IRAK4 (0.35) | HPGDIRAK4 | |
| SCHEMBL24329024 | 0.82 | HPGD (0.36) | HPGDIRAK4WNT1GSK3BDYRK1A | |
| SCHEMBL23680881 | 0.81 | HPGD (0.36) | HPGDIRAK4WNT1GSK3BDYRK1A | |
| SCHEMBL23680862 | 0.81 | HPGD (0.51) | HPGDMGLL | |
| SCHEMBL24329658 | 0.74 | PTK2 (0.40) | HPGD | |
| SCHEMBL24328730 | 0.72 | IRAK4 (0.45) | IRAK4 | |
| SCHEMBL24328714 | 0.72 | IRAK4 (0.37) | HPGDIRAK4MGLL | |
| SCHEMBL23680706 | 0.71 | HPGD (0.54) | HPGDMGLL | |
| SCHEMBL24329022 | 0.70 | HPGD (0.39) | HPGDIRAK4MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022082009-A1 | INHALED FORMULATIONS OF PGDH INHIBITORS AND METHODS OF USE THEREOF | EPIRIUM BIO INC. (US) | 2022-04-21 | — | — | WO | disclosed |