Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 17/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29555248 | 1.00 | GLP1R (0.43) | GLP1RKCNH2HTR6SLC6A2SLC6A4 | |
| SCHEMBL24485665 | 0.89 | HTR6 (0.54) | GLP1RKCNH2HTR6SLC6A2SLC6A4 | |
| SCHEMBL30149360 | 0.89 | HTR6 (0.54) | GLP1RKCNH2HTR6SLC6A2SLC6A4 | |
| SCHEMBL24485288 | 0.87 | GLP1R (0.43) | GLP1RKCNH2HTR6SLC6A2SLC6A4 | |
| SCHEMBL20267985 | 0.87 | GLP1R (0.55) | GLP1RKCNH2 | |
| SCHEMBL30149289 | 0.87 | GLP1R (0.43) | GLP1RKCNH2HTR6SLC6A2SLC6A4 | |
| SCHEMBL30951873 | 0.87 | GLP1R (0.43) | GLP1RKCNH2HTR6SLC6A2SLC6A4 | |
| SCHEMBL24321924 | 0.87 | HTR6 (0.47) | GLP1RKCNH2HTR6SLC6A2SLC6A4 | |
| SCHEMBL29394844 | 0.87 | GLP1R (0.55) | GLP1RKCNH2 | |
| Hydrochloric Acid SCHEMBL25286836 | 0.86 | GLP1R (0.54) | GLP1RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4227299-A1 | BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF | Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. (CN) | 2023-08-16 | — | — | EP | disclosed |
| EP-4227299-A1 | BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF | Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. (CN) | 2023-08-16 | — | — | EP | disclosed |
| CN-116348464-A | Benzimidazolone GLP-1 receptor agonists and uses thereof | 杭州中美华东制药有限公司 | 2023-06-27 | — | — | CN | disclosed |
| WO-2022078152-A1 | BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF | 杭州中美华东制药有限公司 | 2022-04-21 | — | — | WO | disclosed |