Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.54 |
| ▸ | GLP1R | P43220 | 13/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24485665 | 1.00 | HTR6 (0.54) | HTR6GLP1RSLC6A2SLC6A4SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL30583928 | 0.91 | GLP1R (0.53) | HTR6GLP1R | |
| SCHEMBL30149255 | 0.91 | GLP1R (0.51) | HTR6GLP1RSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24485480 | 0.91 | GLP1R (0.51) | HTR6GLP1RSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30951873 | 0.89 | GLP1R (0.43) | HTR6GLP1RSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24321924 | 0.89 | HTR6 (0.47) | HTR6GLP1RSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24485288 | 0.89 | GLP1R (0.43) | HTR6GLP1RSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20267985 | 0.89 | GLP1R (0.55) | GLP1RKCNH2 | |
| SCHEMBL24329238 | 0.89 | GLP1R (0.43) | HTR6GLP1RSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30149289 | 0.89 | GLP1R (0.43) | HTR6GLP1RSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461334-B | Benzimidazole derivative, and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-115461334-A | Benzimidazole derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-12-09 | — | — | CN | disclosed |