Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.69 |
| ▸ | NPC1 | O15118 | 11/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.69 |
| ▸ | HTT | P42858 | 6/20 | 0.69 |
| ▸ | PKM | P14618 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.66 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | SCD | O00767 | 2/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6229312 | 0.86 | NPC1 (0.76) | RAB9ANPC1SMN1; SMN2HTTPKM | |
| SCHEMBL26884020 | 0.80 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2HTTPKM | |
| SCHEMBL19270374 | 0.79 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2HTTPKM | |
| SCHEMBL26884209 | 0.78 | NPC1 (0.51) | RAB9ANPC1SMN1; SMN2HTTPKM | |
| SCHEMBL17987824 | 0.78 | HSP90AA1 (0.59) | RAB9ANPC1SMN1; SMN2HTTMAPT | |
| SCHEMBL26645981 | 0.77 | ROCK2 (0.56) | RAB9ANPC1SMN1; SMN2HTTPKM | |
| SCHEMBL30608755 | 0.77 | NPC1 (0.62) | RAB9ANPC1SMN1; SMN2HTTPKM | |
| SCHEMBL29074213 | 0.77 | NPC1 (0.62) | RAB9ANPC1SMN1; SMN2HTTPKM | |
| SCHEMBL26658228 | 0.77 | RAB9A (0.82) | RAB9ANPC1SMN1; SMN2HTTPKM | |
| SCHEMBL24329695 | 0.77 | RAB9A (0.60) | RAB9ANPC1SMN1; SMN2HTTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382903-A1 | SMALL MOLECULE MODULATORS OF GP130 SIGNALING PATHWAYS, TOPICAL FORMULATIONS AND METHOD OF USE THEREOF | CARTHRONIX INC (US) | 2023-11-30 | — | — | US | disclosed |
| US-20230382903-A1 | SMALL MOLECULE MODULATORS OF GP130 SIGNALING PATHWAYS, TOPICAL FORMULATIONS AND METHOD OF USE THEREOF | CARTHRONIX INC (US) | 2023-11-30 | — | — | US | disclosed |
| WO-2022082071-A1 | SMALL MOLECULE MODULATORS OF GP130 SIGNALING PATHWAYS, TOPICAL FORMULATIONS AND METHOD OF US THEREOF | CARTHRONIX, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382903-A1 | SMALL MOLECULE MODULATORS OF GP130 SIGNALING PATHWAYS, TOPICAL FORMULATIONS AND METHOD OF USE THEREOF | STAT1, STAT3, STAT6 | RAB9A 3504/4885NPC1 2133/4885SMN1; SMN2 4696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.