Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 15/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2032778 | 0.85 | SIRT2 (0.47) | SIRT2CYP11B1CYP11B2 | |
| SCHEMBL24329385 | 0.83 | SIRT2 (0.44) | SIRT2KDM4EALDH1A1 | |
| SCHEMBL4391915 | 0.82 | SIRT2 (0.42) | SIRT2 | |
| Lithium Ion SCHEMBL18991219 | 0.82 | SIRT2 (0.45) | SIRT2CYP11B1CYP11B2 | |
| SCHEMBL4682888 | 0.81 | SIRT2 (0.46) | SIRT2CYP11B1CYP11B2 | |
| SCHEMBL7705343 | 0.80 | SIRT2 (0.46) | SIRT2CYP11B1CYP11B2 | |
| SCHEMBL4389525 | 0.80 | LMNA (0.47) | SIRT2MAPT | |
| SCHEMBL24329386 | 0.78 | SIRT2 (0.36) | SIRT2KDM4EALDH1A1 | |
| SCHEMBL1041048 | 0.76 | SIRT2 (0.49) | SIRT2CYP11B1CYP11B2 | |
| SCHEMBL7988579 | 0.74 | CYP11B1 (0.44) | SIRT2CYP11B1CYP11B2LTA4HEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022079428-A1 | LINEAR APELIN RECEPTOR AGONISTS | HEPTARES THERAPEUTICS LIMITED (GB) | 2022-04-21 | — | — | WO | disclosed |