Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 14/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7084063 | 0.89 | SIRT2 (0.43) | SIRT2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL3976810 | 0.81 | SIRT2 (0.45) | SIRT2 | |
| SCHEMBL4389525 | 0.80 | LMNA (0.47) | SIRT2LMNA | |
| SCHEMBL24329384 | 0.78 | SIRT2 (0.41) | SIRT2KDM4EALDH1A1 | |
| SCHEMBL24329385 | 0.76 | SIRT2 (0.44) | SIRT2KDM4EALDH1A1LMNAALOX15 | |
| SCHEMBL4391915 | 0.75 | SIRT2 (0.42) | SIRT2TSHR | |
| SCHEMBL5439663 | 0.74 | SIRT2 (0.42) | SIRT2 | |
| SCHEMBL10914340 | 0.71 | KDM4E (0.33) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL3821641 | 0.70 | SIRT2 (0.46) | SIRT2 | |
| SCHEMBL1039638 | 0.70 | SIRT2 (0.43) | SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022079428-A1 | LINEAR APELIN RECEPTOR AGONISTS | HEPTARES THERAPEUTICS LIMITED (GB) | 2022-04-21 | — | — | WO | disclosed |