SCHEMBL24329410

SCHEMBL24329410

CC(=O)OC[C@H]1COc2ccc(C#N)cc2O1

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 16/20 0.57
L3MBTL1 Q9Y468 2/20 0.47
MAPK1 P28482 1/20 0.47
MTNR1A P48039 2/20 0.45
CYP2C9 P11712 1/20 0.42
CYP2B6 P20813 1/20 0.42
SLCO1B3 Q9NPD5 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19776224 0.83 CA2 (0.54) FFAR1L3MBTL1MAPK1MTNR1A
SCHEMBL19776040 0.83 CA2 (0.54) FFAR1L3MBTL1MAPK1MTNR1A
SCHEMBL19776284 0.82 DRD2 (0.54) FFAR1L3MBTL1MAPK1MTNR1A
SCHEMBL19776654 0.82 DRD2 (0.54) FFAR1L3MBTL1MAPK1MTNR1A
SCHEMBL19776291 0.82 FFAR1 (0.54) FFAR1L3MBTL1MAPK1MTNR1ACYP2C9
SCHEMBL19776202 0.82 FFAR1 (0.54) FFAR1L3MBTL1MAPK1MTNR1ACYP2C9
SCHEMBL6740016 0.81 FFAR1 (0.51) FFAR1MTNR1ACYP2C9CYP2B6SLCO1B3
SCHEMBL6738922 0.81 FFAR1 (0.49) FFAR1L3MBTL1
SCHEMBL15865348 0.81 FFAR1 (0.49) FFAR1L3MBTL1
SCHEMBL15865467 0.81 FFAR1 (0.49) FFAR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250145634-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-05-08 US disclosed
US-20240058340-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER ERASCA, INC. 2024-02-22 US disclosed
US-20230364091-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-11-16 US disclosed
US-20230364091-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-11-16 US disclosed
US-20230364091-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-11-16 US disclosed
CN-115215808-A Compositions and methods for treating cancer 加利福尼亚大学董事会 2022-10-21 CN disclosed
US-11377451-B2 Compositions and methods for treating cancer THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-07-05 US disclosed
US-11377451-B2 Compositions and methods for treating cancer THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-07-05 US disclosed
WO-2022061202-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-03-24 WO disclosed
WO-2022061202-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-03-24 WO disclosed
WO-2022061201-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-03-24 WO disclosed
US-20220064177-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-03-03 US disclosed
US-20220064177-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-03-03 US disclosed
CN-113811528-A Compositions and methods for treating cancer 加利福尼亚大学董事会 2021-12-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250145634-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER TP53, SLC2A1, EGFR FFAR1 2846/4885L3MBTL1 3738/4885MAPK1 1392/4885
US-11377451-B2 Compositions and methods for treating cancer TP53, EGFR, SLC2A1 FFAR1 3500/4885L3MBTL1 3700/4885MAPK1 1416/4885
US-20230364091-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER TP53, EGFR, SLC2A1 FFAR1 3096/4885L3MBTL1 3803/4885MAPK1 1531/4885
US-20220064177-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER TP53, SLC2A1, EGFR FFAR1 2846/4885L3MBTL1 3738/4885MAPK1 1392/4885
US-20240058340-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER TP53, EGFR, SLC2A1 FFAR1 3096/4885L3MBTL1 3803/4885MAPK1 1531/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.