Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.49 |
| ▸ | GLP1R | P43220 | 7/20 | 0.43 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24329294 | 0.89 | TRPV3 (0.45) | GPR119GLP1RTRPV3PRMT5MAPT | |
| SCHEMBL24329295 | 0.89 | GLP1R (0.49) | GLP1RTRPV3PRMT5MAPTSMN1; SMN2 | |
| SCHEMBL24329269 | 0.89 | GLP1R (0.47) | GPR119GLP1RTRPV3PRMT5MAPT | |
| SCHEMBL24329805 | 0.88 | GPR119 (0.48) | GPR119GLP1RTRPV3 | |
| SCHEMBL24330292 | 0.88 | GPR119 (0.48) | GPR119GLP1RTRPV3 | |
| SCHEMBL24329267 | 0.86 | GLP1R (0.48) | GPR119GLP1R | |
| SCHEMBL29554818 | 0.86 | GPR119 (0.48) | GPR119GLP1RTRPV3 | |
| SCHEMBL29555062 | 0.86 | GLP1R (0.48) | GPR119GLP1R | |
| SCHEMBL24329524 | 0.86 | GPR119 (0.48) | GPR119GLP1RTRPV3 | |
| SCHEMBL25340508 | 0.86 | GPR119 (0.55) | GPR119GLP1RTRPV3PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4227299-A1 | BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF | Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. (CN) | 2023-08-16 | — | — | EP | disclosed |
| WO-2022078152-A1 | BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF | 杭州中美华东制药有限公司 | 2022-04-21 | — | — | WO | disclosed |