Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25001244 | 0.82 | TP53 (0.60) | SMN1; SMN2TP53ALDH1A1MEN1KMT2A | |
| SCHEMBL19252750 | 0.80 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL3029049 | 0.80 | SMN1; SMN2 (0.64) | SMN1; SMN2TP53ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL21320757 | 0.76 | ALDH1A1 (0.46) | SMN1; SMN2TP53ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL14006090 | 0.76 | ALDH1A1 (0.46) | SMN1; SMN2TP53ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3031783 | 0.76 | ATM (0.51) | SMN1; SMN2TP53ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL24330982 | 0.75 | SMN1; SMN2 (0.63) | SMN1; SMN2TP53ALDH1A1MEN1KMT2A | |
| SCHEMBL28080097 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2TP53ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL26482560 | 0.74 | TP53 (0.51) | SMN1; SMN2TP53ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL24329884 | 0.72 | MEN1 (0.51) | SMN1; SMN2TP53ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078403-A1 | SUBSTITUTED PYRIDONE COMPOUND AND APPLICATION | 江苏先声药业有限公司 | 2022-04-21 | — | — | WO | disclosed |