Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19808001 | 0.91 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDHSD17B10HTR3A | |
| SCHEMBL831803 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10TGFBR1 | |
| SCHEMBL30525511 | 0.81 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDHSD17B10TGFBR1 | |
| SCHEMBL24329882 | 0.81 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDHSD17B10TGFBR1 | |
| SCHEMBL31249024 | 0.76 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10PARP1 | |
| SCHEMBL19807936 | 0.76 | SMN1; SMN2 (0.41) | KDM4EALDH1A1HTR3AIKBKBHRH4 | |
| SCHEMBL21321091 | 0.76 | TGFBR1 (0.40) | KDM4EALDH1A1HPGDHSD17B10TGFBR1 | |
| SCHEMBL13057965 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10TGFBR1 | |
| SCHEMBL19807935 | 0.72 | ALPI (0.40) | KDM4EALDH1A1HSD17B10HTR3AMAPK1 | |
| SCHEMBL831804 | 0.71 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078403-A1 | SUBSTITUTED PYRIDONE COMPOUND AND APPLICATION | 江苏先声药业有限公司 | 2022-04-21 | — | — | WO | disclosed |