SCHEMBL24329611

SCHEMBL24329611

Cc1cc(COc2cccc(C3CCN(C(=O)OC(C)(C)C)CC3)n2)c(F)cc1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 20/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29554848 1.00 GLP1R (0.49) GLP1R
SCHEMBL24329559 0.92 TRPV3 (0.44) GLP1R
SCHEMBL24329329 0.92 GLP1R (0.47) GLP1R
SCHEMBL24329806 0.90 GLP1R (0.47) GLP1R
SCHEMBL29555590 0.90 GLP1R (0.47) GLP1R
SCHEMBL24329805 0.89 GPR119 (0.48) GLP1R
SCHEMBL29556019 0.88 GLP1R (0.58) GLP1R
SCHEMBL25339441 0.88 GLP1R (0.58) GLP1R
SCHEMBL24329293 0.88 GLP1R (0.58) GLP1R
SCHEMBL29555029 0.88 GLP1R (0.58) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4227299-A1 BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. (CN) 2023-08-16 EP disclosed
EP-4227299-A1 BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. (CN) 2023-08-16 EP disclosed
CN-116348464-A Benzimidazolone GLP-1 receptor agonists and uses thereof 杭州中美华东制药有限公司 2023-06-27 CN disclosed
WO-2022078152-A1 BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF 杭州中美华东制药有限公司 2022-04-21 WO disclosed