Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPM1 | P06748 | 3/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30525520 | 1.00 | HPGD (0.37) | HPGDALDH1A1NPM1ALKTP53 | |
| SCHEMBL24329594 | 0.81 | SMN1; SMN2 (0.44) | ALDH1A1NOTUMAURKAMAPTSMN1; SMN2 | |
| SCHEMBL9255441 | 0.76 | ALDH1A1 (0.53) | HPGDALDH1A1NOTUMMEN1KMT2A | |
| SCHEMBL17531765 | 0.76 | MAPT (0.43) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL946355 | 0.70 | NOTUM (0.62) | HPGDALDH1A1TP53CLK1NOTUM | |
| SCHEMBL21320757 | 0.69 | ALDH1A1 (0.46) | HPGDALDH1A1TP53MEN1KMT2A | |
| SCHEMBL24329884 | 0.68 | MEN1 (0.51) | HPGDALDH1A1TP53MEN1KMT2A | |
| SCHEMBL7484548 | 0.67 | ALDH1A1 (0.50) | HPGDALDH1A1NOTUMMEN1KMT2A | |
| SCHEMBL422637 | 0.65 | HTT (0.42) | HPGDALDH1A1NPM1ALKTP53 | |
| SCHEMBL31228880 | 0.65 | HTT (0.42) | ALDH1A1NPM1ALKMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078403-A1 | SUBSTITUTED PYRIDONE COMPOUND AND APPLICATION | 江苏先声药业有限公司 | 2022-04-21 | — | — | WO | disclosed |