SCHEMBL2433108

SCHEMBL2433108

CC(C)c1cc2c(c(C(C)C)c1)O[PH](=O)c1cc(C(C)C)ccc1-2

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
FABP3 P05413 2/20 0.33
FABP4 P15090 2/20 0.33
FABP5 Q01469 1/20 0.32
KLK7 P49862 1/20 0.31
CTRC Q99895 1/20 0.31
TYR P14679 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30
TRPA1 O75762 1/20 0.30
PTGS1 P23219 1/20 0.30
CACNA1C Q13936 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2437545 0.86 FABP3 (0.33) FABP3FABP4FABP5GABRA1GABRB2
SCHEMBL2466854 0.78 TYR (0.32) TYR
SCHEMBL2425950 0.74 LMNA (0.36) LMNATYR
SCHEMBL2435971 0.68 NR1H3 (0.36) LMNATYRTRPA1PTGS1CACNA1C
SCHEMBL2434723 0.67 DPP4 (0.38) LMNAGABRA1GABRB2PTGS1
SCHEMBL2425867 0.67 LMNA (0.36) LMNAFABP3FABP4FABP5GABRA1
SCHEMBL2427489 0.61 NQO1 (0.36)
SCHEMBL598620 0.60 LMNA (0.60) LMNAFABP3FABP4FABP5TYR
SCHEMBL13160119 0.60 LMNA (0.60) LMNATYRTRPA1PTGS1CACNA1C
SCHEMBL28520925 0.60 LMNA (0.60) LMNATYRTRPA1PTGS1CACNA1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8592071-B2 Laminated porous film and separator for battery MITSUBISHI PLASTICS, INC. (JP) 2013-11-26 US disclosed
EP-2550063-A1 ALR2 INHIBITORS AND THEIR SYNTHESIS FROM A NATURAL SOURCE Council of Scientific & Industrial Research (IN) 2013-01-30 EP disclosed
WO-2011117706-A1 ALR2 INHIBITORS AND THEIR SYNTHESIS FROM A NATURAL SOURCE COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2011-09-29 WO disclosed
US-20110212358-A1 LAMINATED POROUS FILM AND SEPARATOR FOR BATTERY MITSUBISHI PLASTICS, INC. (JP) 2011-09-01 US disclosed
EP-0790262-B1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORP (JP) 2000-05-10 EP disclosed
US-6005034-A POLYMER MELTS OF ETHYLENE-PROPYLENE COPOLYMERS CHISSO CORPOATION (JP) 1999-12-21 US disclosed
EP-0790262-A1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORPORATION (JP) 1997-08-20 EP disclosed