SCHEMBL2425950

SCHEMBL2425950

CC(C)c1ccc2c(c1)[PH](=O)Oc1ccccc1-2

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
PDK2 Q15119 1/20 0.35
NR1H3 Q13133 1/20 0.33
TYR P14679 1/20 0.32
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
KIF11 P52732 1/20 0.31
TNKS O95271 1/20 0.30
TNKS2 Q9H2K2 1/20 0.30
PARP3 Q9Y6F1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2431667 0.87 DAO (0.31)
SCHEMBL2431076 0.86 HDAC4 (0.35) LMNAUSP2MAPT
SCHEMBL2435971 0.85 NR1H3 (0.36) LMNAPDK2NR1H3TYRMEN1
SCHEMBL2438109 0.80 ELANE (0.42) LMNAPDK2
SCHEMBL29395467 0.76 HSP90AA1 (0.35)
SCHEMBL29363087 0.76 HSP90AA1 (0.35)
SCHEMBL30781 0.76 HSP90AA1 (0.35)
SCHEMBL2428112 0.76 MAPT (0.46) LMNAPDK2MEN1MAPTKMT2A
SCHEMBL28498907 0.76 GPR3 (0.41) MAPT
SCHEMBL31183036 0.75 HSP90AA1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8592071-B2 Laminated porous film and separator for battery MITSUBISHI PLASTICS, INC. (JP) 2013-11-26 US disclosed
US-20110212358-A1 LAMINATED POROUS FILM AND SEPARATOR FOR BATTERY MITSUBISHI PLASTICS, INC. (JP) 2011-09-01 US disclosed
EP-0790262-B1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORP (JP) 2000-05-10 EP disclosed
US-6005034-A POLYMER MELTS OF ETHYLENE-PROPYLENE COPOLYMERS CHISSO CORPOATION (JP) 1999-12-21 US disclosed
EP-0790262-A1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORPORATION (JP) 1997-08-20 EP disclosed