Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29515233 | 0.91 | GHSR (0.32) | PIK3CDSCN9APARP14BACE1CNR2 | |
| SCHEMBL24331179 | 0.91 | GHSR (0.32) | PIK3CDSCN9APARP14BACE1CNR2 | |
| SCHEMBL26125431 | 0.83 | HTR2C (0.33) | PIK3CD | |
| SCHEMBL30588779 | 0.83 | HTR2C (0.33) | PIK3CD | |
| SCHEMBL24331315 | 0.82 | LCK (0.35) | — | |
| SCHEMBL24332194 | 0.74 | LCK (0.33) | — | |
| SCHEMBL29515085 | 0.73 | LCK (0.31) | PIK3CD | |
| SCHEMBL24332233 | 0.73 | LCK (0.31) | PIK3CD | |
| SCHEMBL24332258 | 0.72 | NQO2 (0.31) | PIK3CD | |
| SCHEMBL24331390 | 0.72 | ADORA3 (0.31) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076620-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |