Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | CCNK | O75909 | 1/20 | 0.43 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24330400 | 0.94 | CNR1 (0.49) | CNR1HTTMAPTGPR119KDM4E | |
| SCHEMBL26911627 | 0.86 | HPGDS (0.49) | PDE4BCNR1HTTMAPTGPR119 | |
| SCHEMBL31295106 | 0.86 | HPGDS (0.49) | PDE4BCNR1HTTMAPTGPR119 | |
| SCHEMBL24330049 | 0.85 | HTT (0.49) | CNR1HTTMAPTGPR119KDM4E | |
| SCHEMBL24330047 | 0.82 | BRD3 (0.51) | CNR1HTTMAPTKDM4ETHRB | |
| SCHEMBL18547676 | 0.81 | CNR1 (0.48) | PDE4BCNR1HTTMAPTGPR119 | |
| SCHEMBL31358139 | 0.81 | JAK2 (0.54) | CNR1GPR119KDM4EJAK2JAK1 | |
| SCHEMBL14211589 | 0.80 | HSD11B1 (0.52) | PDE4BMAPTGPR119KDM4ETHRB | |
| SCHEMBL18548033 | 0.80 | CNR1 (0.49) | PDE4BCNR1HTTMAPTGPR119 | |
| SCHEMBL29468210 | 0.79 | JAK2 (0.52) | CNR1HTTMAPTGPR119KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078971-A1 | NOVEL COMPOUNDS | AC IMMUNE SA (CH) | 2022-04-21 | — | — | WO | disclosed |