SCHEMBL2433218

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2428610	1.00	ABL1 (0.40)	ABL1DGAT1SLC6A3TAAR1ACKR3
	SCHEMBL2431395	0.89	DGAT1 (0.40)	DGAT1ACKR3MAPTGSK3B
	SCHEMBL2431392	0.89	DGAT1 (0.40)	DGAT1ACKR3MAPTGSK3B
	SCHEMBL2432215	0.86	NPC1 (0.43)	DGAT1MAPTTHRB
	SCHEMBL2434383	0.86	NPC1 (0.43)	DGAT1MAPTTHRB
	SCHEMBL2430782	0.86	MEN1 (0.48)	DGAT1MAPTTHRB
	SCHEMBL2430785	0.86	MEN1 (0.48)	DGAT1MAPTTHRB
	SCHEMBL2432191	0.86	ACKR3 (0.41)	DGAT1ACKR3MAPTGSK3B
	SCHEMBL2432190	0.86	DGAT1 (0.35)	DGAT1
	SCHEMBL2431901	0.86	DGAT1 (0.35)	DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.