SCHEMBL2431392

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2431395	1.00	DGAT1 (0.40)	DGAT1ACKR3MAPTGSK3BNPC1
	SCHEMBL2434383	0.90	NPC1 (0.43)	DGAT1MAPTNPC1GAARAB9A
	SCHEMBL2432215	0.90	NPC1 (0.43)	DGAT1MAPTNPC1GAARAB9A
	SCHEMBL2428610	0.89	ABL1 (0.40)	DGAT1ACKR3MAPTGSK3B
	SCHEMBL2433218	0.89	ABL1 (0.40)	DGAT1ACKR3MAPTGSK3B
	SCHEMBL2431201	0.87	ACKR3 (0.41)	DGAT1ACKR3MAPTGSK3B
	SCHEMBL2432191	0.87	ACKR3 (0.41)	DGAT1ACKR3MAPTGSK3B
	SCHEMBL2428609	0.87	PTPN2 (0.42)	DGAT1ACKR3MAPTNPC1RAB9A
	SCHEMBL2432620	0.87	PTPN2 (0.42)	DGAT1ACKR3MAPTNPC1RAB9A
	SCHEMBL2429418	0.86	DHX9 (0.40)	DGAT1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.