Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 15/20 | 0.44 |
| ▸ | DCLK1 | O15075 | 14/20 | 0.44 |
| ▸ | MAPK7 | Q13164 | 13/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.44 |
| ▸ | TNK1 | Q13470 | 2/20 | 0.44 |
| ▸ | DCLK2 | Q8N568 | 2/20 | 0.44 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.44 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.44 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | GAK | O14976 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30876812 | 0.99 | LRRK2 (0.43) | LRRK2DCLK1MAPK7BRD4TNK2 | |
| SCHEMBL24334550 | 0.91 | LRRK2 (0.41) | LRRK2DCLK1MAPK7BRD4TNK2 | |
| SCHEMBL24306754 | 0.89 | LRRK2 (0.59) | LRRK2DCLK1MAPK7BRD4TNK2 | |
| SCHEMBL27196763 | 0.89 | MAPK7 (0.39) | LRRK2DCLK1MAPK7BRD4TNK2 | |
| Hydrochloric Acid SCHEMBL30876803 | 0.88 | LRRK2 (0.59) | LRRK2DCLK1MAPK7BRD4TNK2 | |
| SCHEMBL24334582 | 0.88 | MAPK7 (0.41) | LRRK2DCLK1MAPK7BRD4TNK2 | |
| SCHEMBL24334116 | 0.86 | LRRK2 (0.43) | LRRK2DCLK1MAPK7BRD4TNK2 | |
| SCHEMBL27196681 | 0.86 | MAPK7 (0.38) | LRRK2DCLK1MAPK7BRD4TNK2 | |
| SCHEMBL24334772 | 0.85 | LRRK2 (0.57) | LRRK2DCLK1MAPK7BRD4TNK2 | |
| SCHEMBL24334585 | 0.85 | LRRK2 (0.56) | LRRK2DCLK1MAPK7BRD4TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124460-A1 | METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION | RANOK THERAPEUTICS (HANGZHOU) CO. LTD. (CN) | 2024-04-18 | — | — | US | disclosed |
| WO-2022078350-A1 | METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION | RANOK THERAPEUTICS (HANGZHOU) CO. LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240124460-A1 | METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION | PSMG3, PSMC2, PSMA6 | LRRK2 1277/4885DCLK1 2928/4885MAPK7 1599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.