Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15986990 | 0.83 | USP2 (0.46) | USP2ALDH1A1CYP2C19MAPK1MEN1 | |
| SCHEMBL26783934 | 0.82 | USP2 (0.60) | USP2ALDH1A1CYP2C19MAPK1MEN1 | |
| SCHEMBL18711766 | 0.82 | USP2 (0.45) | USP2ALDH1A1CYP2C19MAPK1MEN1 | |
| SCHEMBL26510453 | 0.82 | CYP2C9 (0.45) | USP2ALDH1A1CYP2C19MAPK1MEN1 | |
| SCHEMBL15155193 | 0.81 | HRH3 (0.33) | USP2ALDH1A1CYP2C19MAPK1MEN1 | |
| SCHEMBL15544126 | 0.80 | USP2 (0.58) | USP2ALDH1A1CYP2C19MAPK1MEN1 | |
| SCHEMBL18913868 | 0.79 | OPRM1 (0.41) | ALDH1A1CYP1A2EPHX2 | |
| SCHEMBL29324699 | 0.79 | EPHX2 (0.45) | USP2ALDH1A1CYP2C19MAPK1MEN1 | |
| SCHEMBL23468394 | 0.79 | CHRNB2 (0.39) | ALDH1A1CYP2C19MEN1KMT2ACYP2C9 | |
| SCHEMBL24607223 | 0.79 | CYP2D6 (0.43) | USP2ALDH1A1CYP2C19MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023205701-A1 | MACROCYCLIC HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| EP-3380469-B1 | BICYCLIC BET BROMODOMAIN INHIBITORS AND USES THEREOF | CONVERGENE LLC (US) | 2022-03-16 | — | — | EP | disclosed |