Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 3/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.32 |
| ▸ | MAP2 | P11137 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29469663 | 1.00 | PTGDR (0.35) | PTGDRSLC6A9ALDH1A1RXFP1LMNA | |
| SCHEMBL29469691 | 0.91 | ALDH1A1 (0.42) | ALDH1A1LMNAKMT2AMAPTKDM4E | |
| SCHEMBL29469724 | 0.90 | MAPT (0.39) | PTGDRALDH1A1RXFP1LMNADRD2 | |
| SCHEMBL24333981 | 0.90 | MAPT (0.39) | PTGDRALDH1A1RXFP1LMNADRD2 | |
| SCHEMBL24333713 | 0.89 | MEN1 (0.37) | PTGDRALDH1A1RXFP1LMNADRD2 | |
| SCHEMBL24333774 | 0.89 | ALDH1A1 (0.44) | ALDH1A1LMNAKMT2AMAPTHSD17B10 | |
| SCHEMBL24334437 | 0.88 | KMT2A (0.38) | PTGDRALDH1A1RXFP1DRD2ADRA1D | |
| SCHEMBL29469684 | 0.88 | ALDH1A1 (0.36) | ALDH1A1LMNATRPV1 | |
| SCHEMBL24334016 | 0.88 | ALDH1A1 (0.36) | ALDH1A1LMNATRPV1 | |
| SCHEMBL24334344 | 0.87 | KCNH2 (0.38) | ALDH1A1LMNAKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081807-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |