Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.52 |
| ▸ | VCP | P55072 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24335037 | 0.84 | IKBKB (0.44) | PTGS2PTGS1ATRLOXL2 | |
| SCHEMBL24335191 | 0.83 | PTGS2 (0.59) | PTGS2PTGS1VCP | |
| SCHEMBL24334957 | 0.82 | PTGS2 (0.59) | PTGS2PTGS1VCP | |
| SCHEMBL22828104 | 0.78 | PTGS2 (0.75) | PTGS2PTGS1 | |
| SCHEMBL24334941 | 0.76 | PTGS2 (0.75) | PTGS2PTGS1 | |
| SCHEMBL24334904 | 0.74 | PTGS2 (0.62) | PTGS2 | |
| SCHEMBL22828091 | 0.69 | PTGS2 (0.57) | PTGS2PTGS1VCP | |
| SCHEMBL5787610 | 0.68 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL24335036 | 0.66 | PTGS2 (0.83) | PTGS2PTGS1 | |
| SCHEMBL5791089 | 0.65 | PTGS2 (0.66) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220106275-A1 | RADIOLABELED COMPOUNDS AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2022-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220106275-A1 | RADIOLABELED COMPOUNDS AND USES THEREOF | PAICS, TMEM14C, SLCO1B1 | PTGS2 4365/4885PTGS1 3758/4885VCP 2797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.