SCHEMBL24335031

SCHEMBL24335031

CCSC(C)C(=O)[C@@H](CCCNC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](CS(=O)(=O)O)NC(=O)CCCCCN1C(=O)C=CC1=O)C(C)C

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ FAP Q12884 3/20 0.34
▸ NPY5R Q15761 5/20 0.33
▸ NPY4R P50391 5/20 0.33
▸ NPY1R P25929 4/20 0.33
▸ CTSL P07711 1/20 0.33
▸ NPY2R P49146 2/20 0.33
▸ TLR2 O60603 1/20 0.32
▸ FURIN P09958 5/20 0.32
▸ PRSS1 P07477 1/20 0.32
▸ KISS1R Q969F8 1/20 0.30
▸ NMT2 O60551 1/20 0.30
▸ NMT1 P30419 1/20 0.30
▸ PTGS1 P23219 2/20 0.30
▸ PTGS2 P35354 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20864068 0.92 NPY5R (0.35) FAPNPY5RNPY4RNPY1RCTSL
SCHEMBL18909056 0.92 NPY5R (0.35) FAPNPY5RNPY4RNPY1RCTSL
SCHEMBL20887767 0.89 FURIN (0.35) FAPNPY5RNPY4RNPY1RCTSL
SCHEMBL17722913 0.89 NPY5R (0.37) FAPNPY5RNPY4RNPY1RCTSL
SCHEMBL22668644 0.87 FAP (0.34) FAPNPY5RNPY4RNPY1RCTSL
SCHEMBL23436443 0.87 FAP (0.34) FAPNPY5RNPY4RNPY1RCTSL
SCHEMBL22668930 0.83 FAP (0.35) FAPNPY5RNPY4RNPY1RCTSL
SCHEMBL23420959 0.82 FAP (0.37) FAPNPY5RNPY4RNPY1RCTSL
SCHEMBL20887736 0.82 FAP (0.37) FAPNPY5RNPY4RNPY1RCTSL
SCHEMBL27433508 0.82 FAP (0.43) FAPNPY5RNPY4RNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220089772-A1 ANTI-GLYCO-MUC1 ANTIBODIES AND THEIR USES GO THERAPEUTICS, INC. (US) 2022-03-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220089772-A1 ANTI-GLYCO-MUC1 ANTIBODIES AND THEIR USES MUC1, SIGLEC7, SIGLEC9 FAP 1009/4885NPY5R 4578/4885NPY4R 4459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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