SCHEMBL243355

SCHEMBL243355

C=C(C)C(=O)CCc1cccc(C(=O)O)c1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 4/20 0.46
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HMGB1 P09429 1/20 0.40
BID P55957 4/20 0.39
MCL1 Q07820 4/20 0.39
BCL2L1 Q07817 3/20 0.39
BAK1 Q16611 3/20 0.39
PPARA Q07869 3/20 0.39
KAT8 Q9H7Z6 2/20 0.39
PPARG P37231 2/20 0.39
EP300 Q09472 1/20 0.39
KAT2A Q92830 1/20 0.39
KAT2B Q92831 1/20 0.39
KAT5 Q92993 1/20 0.39
SAE1 Q9UBE0 1/20 0.39
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
IAPP P10997 1/20 0.37
CLCN2 P51788 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL475829 0.81 CA12 (0.35) FOLH1HTTSMN1; SMN2HMGB1CLCN2
SCHEMBL11202738 0.81 FFAR1 (0.34) FOLH1HTTSMN1; SMN2BIDMCL1
SCHEMBL10599954 0.81 FFAR1 (0.34) FOLH1HTTSMN1; SMN2
SCHEMBL18586489 0.80 FOLH1 (0.53) FOLH1HMGB1BIDMCL1BCL2L1
SCHEMBL22912 0.80 FOLH1 (0.59) FOLH1HMGB1BIDMCL1BCL2L1
SCHEMBL689620 0.79 FOLH1 (0.42) FOLH1HTTSMN1; SMN2HMGB1BID
SCHEMBL36344 0.78 POLB (0.43) FOLH1HTTHMGB1BIDMCL1
SCHEMBL1355661 0.77 BID (0.53) FOLH1HMGB1BIDMCL1BCL2L1
SCHEMBL31319546 0.77 BID (0.53) FOLH1HMGB1BIDMCL1BCL2L1
SCHEMBL4348873 0.77 FOLH1 (0.47) FOLH1HTTSMN1; SMN2HMGB1BID

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1637926-B1 Curable jettable liquid for the production of a flexographic printing plate AGFA GRAPHICS NV (BE) 2009-04-22 EP claimed
EP-1633823-B1 PROCESS FOR ETCHING A METAL OR ALLOY SURFACE FUJIFILM IMAGING COLORANTS LTD (GB) 2008-10-29 EP claimed
EP-1543703-B1 PLATING PROCESS FUJIFILM IMAGING COLORANTS LTD (GB) 2006-09-27 EP claimed
EP-1543083-B1 PROCESS AND INK FOR MAKING ELECTRONIC DEVICES FUJIFILM IMAGING COLORANTS LTD (GB) 2006-08-09 EP claimed
US-11571567-B2 Iontophoresis device for drug delivery and method for manufacturing the same BIOSENSOR LABORATORIES INC. (KR) 2023-02-07 US disclosed
EP-2968090-B1 METHOD OF REMOVING POLYMERIZED COATINGS FROM HUMAN NAILS, POLYMERIZED COATING FOR HUMAN NAILS HAVING IMPROVED REMOVABILITY, AND TWO PACKAGE SYSTEM MYCONE DENTAL SUPPLY COMPANY INC (US) 2021-06-02 EP disclosed
WO-2021085979-A1 APPARATUS USING REVERSE ELECTRODIALYSIS AND REDOX REACTION AND METHOD FOR DELIVERING DRUG BY USING SAME 바이오센서연구소 주식회사 2021-05-06 WO disclosed
US-10945516-B2 Device mounted on mask pack, mask pack and kit comprising the same BIOSENSOR LABORATORIES INC. (KR) 2021-03-16 US disclosed
EP-2525773-B1 EASILY APPLIABLE, STORAGE STABLE, RADIATION-CURABLE, PIGMENTED, ARTIFICIAL NAIL GEL COATINGS MYCONE DENTAL SUPPLY CO INC (US) 2020-02-12 EP disclosed
EP-2547730-B1 METHOD OF PREPARATION OF RADIATION-CURABLE COLORED ARTIFICIAL NAIL GELS MYCONE DENTAL SUPPLY COMPANY INC (US) 2019-07-10 EP disclosed
US-20190151222-A1 ONE PART ARTIFICIAL NAIL SCULPTING COMPOSITIONS AND METHODS WITHOUT REACTIVE OLIGOMERS NAIL ALLIANCE, LLC 2019-05-23 US disclosed
US-20190151223-A1 ONE PART ARTIFICIAL NAIL COMPOSITIONS MYCONE DENTAL SUPPLY CO INC (US) 2019-05-23 US disclosed
US-20070270733-A1 Iontophoresis Device TOKUYAMA CORPORATION (JP) 2007-11-22 US disclosed
US-7272439-B2 Working electrode assembly for iontophoresis and iontophoresis device TOKUYAMA CORPORATION (JP) 2007-09-18 US disclosed
EP-1767243-A1 IONTOPHORESIS APPARATUS Tokuyama Corporation (JP) 2007-03-28 EP disclosed
US-20060183048-A1 Positive photoresist composition and resist pattern formation TOKYO OHKA KOGYO CO., LTD. (JP) 2006-08-17 US disclosed
EP-1664928-A2 POSITIVE PHOTORESIST COMPOSITION AND RESIST PATTERN FORMATION TOKYO OHKA KOGYO CO., LTD. (JP) 2006-06-07 EP disclosed
US-20060089591-A1 Working electrode assembly for iontophoresis and iontophoresis device TOKUYAMA CORPORATION 2006-04-27 US disclosed
EP-1649891-A1 Working electrode assembly for iontophoresis and iontophoresis device Tokuyama Corporation (JP) 2006-04-26 EP disclosed
WO-2005029184-A2 POSITIVE PHOTORESIST COMPOSITION AND RESIST PATTERN FORMATION TOKYO OHKA KOGYO CO., LTD. (JP) 2005-03-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190151223-A1 ONE PART ARTIFICIAL NAIL COMPOSITIONS POLR1C, PIK3C3, NACA FOLH1 3992/4885HTT 163/4885SMN1; SMN2 4474/4885
US-20190151222-A1 ONE PART ARTIFICIAL NAIL SCULPTING COMPOSITIONS AND METHODS WITHOUT REACTIVE OLIGOMERS POLR1C, NACA, SUCLG1 FOLH1 4058/4885HTT 93/4885SMN1; SMN2 4244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.